Heavy Metal 2000 (2000)

Upon discovery of a shard of the Loc-Nar (the evil orb from the 1st Heavy Metal), a miner named Tyler becomes possessed by an insatiable hunger for power & thirst for immortality. On his way to a planet which has a fountain of immortality, Tyler makes a pit stop at F.A.K.K.² (Federation-Assigned Ketogenic Killzone) because its inhabitants carry some immortality water in their bodies. Tyler abducts a few people and kills the rest, but misses one: Julie, the sole survivor enraged by Tyler's careless rampage, vows to avenge her family and kill Tyler before he reaches the fountain.